Opelika is a city in and the county seat of Lee County in the east-central part of the U.S. state of Alabama. It is a principal city of the Auburn-Opelika Metropolitan Area. As of the 2010 census, the population of Opelika was 26,401, and in 2019 the estimated population was 30,908. The Auburn-Opelika, AL MSA with a population of 150,933, along with the Columbus, Georgia metropolitan area, comprises the Greater Columbus combined statistical area,... Show more

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