Piketon is a village in Pike County, Ohio, United States, along the Scioto River. The village is best known for the uranium enrichment plant located there. The population was 2,181 at the 2010 census. Originally called Jefferson, it was the county seat of Pike County 1815–1845, when James Emmitt, a wealthy local entrepreneur, influenced removal of the county seat to Waverly, due to its closer proximity to the then new Ohio & Erie Canal. Piketon... Show more

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