Wytheville is a town in, and the county seat of, Wythe County, in southwestern Virginia, United States. It is named after George Wythe, a signer of the United States Declaration of Independence, and mentor to Thomas Jefferson. Wytheville's population was 8,211 at the 2010 census. Interstate Highways 77 and 81 were constructed to intersect at the town, long a crossroads for travelers. During the American Civil War, Wytheville had a strategic importance.... Show more

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